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Miller et al have found that Sox9 is a promising candidate for distinguishing MPNSTs from other tumour types, and shows differences in the number of positive cells and the degree of nuclear localization in DNFs, PNFs and MPNSTs, suggesting that this marker could aid in grading neurofibromas and MPNSTs.
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Molecular markers could aid to guide therapy in the fit elderly.
To search for a marker that could aid in earlier diagnosis of bowel injury after gynecologic surgery.
Says Steck, "If you had a molecular marker that could aid a clinician in that decision, that would be very significant".
Among the potential molecular markers that could aid in diagnosis or prognosis of EmCa, some such as PKM2, LDHA and cathepsin B have already been explored for their therapeutic potential in other cancers.
This high level of morbidity is thought to be due to an inability to recognize the presence of early stage ovarian cancer in the clinical setting due to the lack of cancer specific markers that could aid early diagnosis and post operative monitoring for disease recurrence.
It is, therefore, crucial to improve the translational effort in order to identify molecular markers that could aid in the prediction of tumour progression, prognosis and therapeutic regimen.
TLR6 may be a potential marker of exposure and could aid in the development of a gene signature for sheep resistant to MAP infection.
A high Pcv aCO2 might identify patients who remain inadequately resuscitated and constitutes a marker of global perfusion that could aid in identifying a hypoperfusion-related hyperlactatemia [12, 13].
It is apparent that SSR markers developed in this study could aid germplasm characterization, construction of genetic linkage maps and comparative mapping in the genus Pistacia.
These methods are rapid, simple and suitable for high throughput screening, and could aid in marker-assisted selection of BLV-resistant and susceptible cattle.
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