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The decreases in the biochemical marker concentrations from baseline were statistically significant when statistical significance was reported.
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Progression was defined as a 20% increase in the diameter of all measured lesions, the appearance of new lesions and/or the doubling of CA125 tumor marker concentration from baseline values.
They found the highest marker concentrations in feces from cows fed with forage.
To determine reproducibility of inflammatory marker concentrations in induced sputum from subjects with cystic fibrosis (CF), 15 nonexpectorating children, 6 to 13 years of age with mild CF lung disease, underwent 3 weekly sputum inductions with 3% saline.
At 6 and 12 weeks, bone marker concentrations were not different from baseline, and no significant differences in bone marker concentrations were observed between treatment groups at either 6 or 12 weeks.
BacR marker concentrations were remarkably similar and showed low variation among samples from all ruminant sources.
Fractional passage rates from the proximal colon-cecum (K2) based on fecal marker concentrations showed trends similar to K1, with Cr-NDF providing a value (0.425/h) more than twice as high as that of 13CDM (0.179/h) and 13CADF (0.128/h).
Although we cannot exclude that the clearance rate of matrix molecules from the joint cavity might influence the associations noted here, marker concentrations were measured long after trauma, and a steady state between markers released into the SF and markers cleared from the SF has likely occurred [ 40].
This study demonstrates the value of this approach in an established model of OA (cranial cruciate ligament rupture) at a point distant enough from the original surgical manipulation so as to have little to no effect on the marker concentrations.
We assumed a log-normal distribution for marker concentrations.
Forty-eight soil samples originating from and close to the catchment area were investigated for BacR and BacH marker concentrations.
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