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F2 individuals were genotyped for one marker close to NOR2, F10A8-12, and one marker close to NOR4, F6N15-34.
The most informative marker close to the peak position of the QTL was used as cofactor in the MQM analysis.
16 In another smaller study, a microsatellite marker close to HLA- C (marker C1_3_2) also showed evidence for an independent effect.
Treating gene expression level as a quantitative trait, roughly a quarter of all gene expression levels were significantly associated with a marker close to the gene itself.
Moreover, LOH analysis of an additional 11 cases, in which loss of this region of CFA 11 was not apparent from aCGH analysis, revealed that six (54%) showed LOH of at least one marker close to the CDKN2A/B locus (data not shown).
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The Lincoln Highway marker closest to New York is in Princeton Township, N.J., on State Highway 27.
RM15206, another marker closed to GS3 also associated with GL in all the six environments.
Almost all of these transgressive segregants had the Kinandang Patong allele of the DNA marker closest to DRO5, suggesting that Kinandang Patong has an allele that decreases RGA.
To compare the mean RDRs in three genotypes for the DNA marker closest to the significant QTL in the three mapping populations, the Tukey's multiple-comparison test function provided in JMP software version 7.0 (SAS Institute Japan, Tokyo, Japan) was used.
First, we estimated the proportion of truly null tests (denoted π0) and truly alternative tests (1−π0) across all 5067 single marker linkage tests performed at the marker closest to the locus of the gene in question.
In the infrequent event of discordance between markers, precedence was given to the marker closest to the APC gene.
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