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We note that in some instances the marker assigned to a drug coincides with what expected given the known drug target (Table 1, Markers and Target columns).
Starting from the existing order of a linkage group, each marker assigned to that linkage group by two-point analysis, but not present on the multi-point map, was tested in every possible location.
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Different markers assigned to the same base position were removed.
Additional file 4: Molecular markers assigned to clones via PCR amplification or microarray hybridization.
Markers assigned to a linkage group were initially ordered using the reduced data set.
We first selected 42 BAC clones that contained markers assigned to 33 RH.
Distorted markers assigned to a LG were randomly distributed (Additional file 4).
DArT markers assigned to their map position were further used to estimate inter- and intra-chromosomal LD.
Next , 2,551DNA markers assigned to 15,683 BACs by overgo hybridization (Methods) were incorporated into the physical map contigs.
BAT SNP markers were added to the latest version of an existing SNP map based on this population [ 17], with the previously mapped markers assigned to a fixed order.
Mapped SNP markers were distributed almost equally across the A and B genomes, with between 279 and 484 markers assigned to each chromosome.
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