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Pathologically, FGF18 is implicated in colorectal (Shimokawa et al., 2003) and ovarian cancer (Wei et al., 2013) and has been proposed as an early marker and potential anticancer drug target.
They also provide significant insight into the immune mechanisms associated to CM by the identification of TBB3 as a new disease-specific marker and potential therapeutic target.
Thus, APEX1 may serve as a prognostic marker and potential therapeutic target for osteosarcoma.
Therefore, miR-20b may be a novel diagnostic marker and potential therapeutic target in breast cancer.
Hence, CP may represent a novel diagnostic marker and potential target for therapeutic intervention in high-risk neuroblastoma patients [ 85].
Our findings suggest that miR-217 has considerable value as a prognostic marker and potential therapeutic target in CRC.
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The aims of the present study were to investigate the effect of such interventions on serum levels of inflammatory markers, and potential associations with changes in serum fatty acids and anthropometric measures.
Gene expression profiling and the analysis of protein-protein interaction (PPI) networks may support the identification of disease bio-markers and potential drug targets.
Ultimately, this type of comparison presents an opportunity for identifying proteins as unique environmental markers and potential broad-based or specific therapeutic targets.
In addition to providing novel insights into the mechanisms of PCa progression, the genes identified here may prove useful as prognostic markers and potential targets for novel therapeutical approaches.
Table 1 compares the colon cancer cases with the matched controls concerning a list of risk markers and potential confounders.
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