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After almost half a century, it is still hard to say what Marker achieved in his masterpiece.
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Under an assumption (null hypothesis) that none of the originally 168 markers are related to MG the probability to see at least one marker achieve this result is only 2.1%.
More critically, none of the plastid markers achieved a rate of correct plant identification greater than 70%, either alone or combined.
No other markers achieved a higher rate of tumors solely positive for one marker.
Despite the higher density of markers in the 1KG, only ~63%% of the markers achieved good quality as compared to 97%% of the HapMap imputed markers.
For gastric cancer, combining even 2 or 3 tumor markers achieved better diagnostic accuracy compared to a single marker alone [ 38, 40].
Four markers achieved genome-wide significance in the unadjusted GWAS, of which three were on chromosome 6 (rs926849; rs2187689; rs7767277) and an intergenic marker on chromosome 3 (rs17034687).
When analysis was restricted to the 53 pTa tumours, none of the individual markers achieved statistical significance for the prediction of subsequent tumour progression.
Membership probabilities, interpreted as proximities of individuals to different clusters [ 48], showed that genome-wide SNP markers achieved unambiguous separation of all groups.
The high density of markers achieved in this ultradense map allowed syntenic studies between lettuce and Vitis vinifera as well as other plant species.
None of the hERG-only block simulated markers achieved such a level of predictive power, and the majority of the most predictive markers are the result of protocols encapsulating prolongation of APD.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com