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In our case, however, the resected adenohypophysis showed markedly widespread ACTH immunopositivity consistent with hyperplasia.
The findings of this study has demonstrated that women with preeclampsia complicated by IUGR had a markedly widespread endothelial dysfunction depicted by the extremely elevated sFlt-1 and reduced PLGF levels compared to normal pregnancy and PE without associated complications (Fig. 2).
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This notion, together with the availability of new less invasive cardiac output measuring devices, has markedly decreased the widespread use of the PAC [ 2].
In fact, drought, famine, and/or crop failure was reported by historical sources during 15 of the 22 periods of epidemic typhus and was described as markedly severe or widespread during the epidemics of 1714, 1785, 1861, 1875, 1884, 1909, and 1915 (J.N. Burns, unpub. data).
"It has caused serious disruptions to economic activities in the kingdom and raises the possibility of widespread violence markedly," said Kim Eng Tan, a credit analyst.
The main finding from the present study is that the dopamine innervation of the thalamus, as evidenced by DAT immunostaining, is markedly denser and more widespread in the macaque monkey than in the rat.
India's economy has slowed markedly over the past year, amid widespread criticism of the political process.
In particular, PECAM-1-immunopositive cells were markedly increased in area over a widespread region around the infarct on the ipsilateral side.
In particular, NGF-immunopositive cells were markedly increased in number over a widespread region around the infarct on the ipsilateral side (Fig. 5a,d).
The widespread introduction of TME has markedly reduced the rate of non-continence-preserving abdominoperineal operations for rectal cancer.
While added trastuzumab increased response and survival rates in each of these strata, combination with anthracyclines unexpectedly increased cardiotoxicity [ 7] (although less markedly with epirubicin [ 8]), impeding its widespread use and favoring taxane-oriented strategies.
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