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This suggests that anti-IL-1 interventions, at least given acutely, may have the capacity to limit injury-amplifying inflammation in the brain without markedly weakening systemic innate immunity needed for host defense.
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It looks inevitable that the fundamentals for consumers will progressively and markedly weaken over the coming months".
But this one, on the highly charged issue of Iran's nuclear program, which the West maintains is geared toward producing weapons, resulted in three weeks of bruising negotiations that ended up producing a markedly weakened final version.
These four characteristic bands were markedly weakened during the degradation reaction, tending to disappear completely after 60 min, without the appearance of new absorption bands in the visible or ultraviolet regions due to destruction of the chromophoric and auxochromic structures by the homogeneous Fenton-like reaction.
The team was markedly weakened for the playoffs with starting goaltender Tomas Vokoun unavailable due to injury and Kariya's linemate Steve Sullivan playing hurt.
Britain answered with further shipbuilding, but by the end of the pre-dreadnought era, British supremacy at sea had markedly weakened.
As a result, the association with HDL cholesterol is markedly weakened (p = 0.014) (Table S2).
The presence of overfitting will markedly weaken the probability that the original findings are reproduced in an independent sample.
Y808A, Y808E and Y808S mutations markedly weakened S1P- and Na3VO4-dependent suppression of GC-B activity, whereas Y808E and Y808S mutations rather elevated cGMP production.
Removal of the BIN1 SH3 domain markedly weakened the BIN1-Tau interaction (Fig. 1d, lanes 4 and 6 vs lanes 3 and 5).
The bone may be markedly weakened if resorption occurs at the interface of the viable and dead bone, or if revascularization and new bone formation in necrotic areas is prevented by the formation of a fibrous scar [ 22].
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CEO of Professional Science Editing for Scientists @ prosciediting.com