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We recently were able to show that such a mechanism operated in the VMH with urocortin locally delivered to the VMH markedly suppressing the counterregulatory response to acute hypoglycemia (57), whereas CRH amplified the response (58).
Only, when Dahl S rats were fed 8% NaCl for 4 weeks did salt significantly enhanced their insulin resistance by markedly suppressing the glucose infusion rate, utilization rate and glucose uptake by the muscles compared to Dahl S rats fed 0.3% NaCl [ 5].
Similar(58)
In addition, pattern collapse was markedly suppressed.
Moreover, GSPE administration markedly suppressed lipid peroxidation.
Fig. 3: Adoptive transfer of GMSCs markedly suppressed the engraftment of donor cells in model two of acute-GVHD.
The nociceptive behavior induced by TAN-67 given i.t. was markedly suppressed by i.t.
Compared with a matched pH buffer, lactic acid markedly suppressed the growth of E coli.
In the presence of TGFβ1, silencing CTGF or Snail1 individually markedly suppressed TGFβ1-induced EMT compared with the NC+TGFβ1 group, as determined by mRNA levels.
Micro-CT results showed disseminated disease in both lungs of the mice treated with vehicle control, whereas ANF markedly suppressed tumor growth (Fig. 6a and supplementary Fig. 3a).
Furthermore, it markedly suppressed the level of TXB2 and up-regulated the level of 6-keto-PGF1a.
Furthermore, treatment with E. coli expressing ClyA markedly suppressed metastatic tumor growth and prolonged the survival time in mice.
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CEO of Professional Science Editing for Scientists @ prosciediting.com