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Consistent with the results of an earlier study, the Boyden chamber assay showed that the migration was markedly suppressed upon antibody blocking.
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This viewpoint is based on the following points: (1) the pK of the ε-amino group of Lys is 10.8 interacting with DNA bases in electrostatics; (2) the interaction between tau and DNA is markedly suppressed at the pH higher than 12, showing dependent upon the electrostatics measured by EMSA; and (3) modification with formaldehyde interferes with the association of tau with DNA.
More importantly, reduction of NFκB1 mRNA markedly suppressed the generation of fibroblast-like cells from RA bone marrow CD34+ cells upon stimulation with SCF, GM-CSF and TNF-α.
In addition, pattern collapse was markedly suppressed.
Moreover, GSPE administration markedly suppressed lipid peroxidation.
The nociceptive behavior induced by TAN-67 given i.t. was markedly suppressed by i.t.
Compared with a matched pH buffer, lactic acid markedly suppressed the growth of E coli.
However, the effects of slr1 on leaf elongation were markedly suppressed in the pla1 and pla2 mutant backgrounds.
Moreover, aged black garlic treatment markedly suppressed the accumulation of lipids and decreased fatty degeneration in mice.
Furthermore, it markedly suppressed the level of TXB2 and up-regulated the level of 6-keto-PGF1a.
Furthermore, treatment with E. coli expressing ClyA markedly suppressed metastatic tumor growth and prolonged the survival time in mice.
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CEO of Professional Science Editing for Scientists @ prosciediting.com