Cells overexpressing Sirt1 showed a markedly stronger immunosignal compared to their untransfected counterparts, which can also be depicted quantitatively as displayed in Figure 3B).
Eighteen and 66 h after the adoptive transfer of sera containing high titers of DNCB-specific Abs into the mice, DNCB challenge of their ears produced a markedly stronger ear swelling compared to animals that received the DNCB-negative sera (Figure 3B).
The images in the frames labeled 440 480 and 490 530 showed a markedly stronger signal and low background compared to the other detection ranges.
As expected, they appear to find that individuals living together have increased similarity in their associated microbial communities, with a markedly stronger effect on skin microbiota, compared to oral or gut microbiotae.
The APC-dependent protein degradation (GO 0031145, full name: Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process) gene-set is characterized by a markedly stronger induction after estrogen treatment at 24 compared to 12 hours (Figure 6, left pane), which is consistent with enrichment results.
- Immunohistochemical in vitro investigations demonstrate that almost every tumor cell of BCCs and SCCs reveals nuclear immunoreactivity for VDR. - In these studies, VDR staining intensity was markedly stronger in both skin tumor types as compared with adjacent epidermis or to distant unaffected epidermis of the same sections.
Subdividing the whole observation interval in two parts before and after 1979, the trend is markedly stronger in the second period with −0.38 K/yr compared with −0.20 K/yr in the first part before 1979.
But looking at a markedly stronger effect of overexpression on mRNA level in transfected Hey cells (230-fold) compared to relatively small changes following CapG knockdown (to 0.25-fold only), the altered migration rate appears to be proportional to the differential CapG expression in the investigated cell lines.
However, when we evaluated the relation of vigorous activity to breast cancer among women who were of normal weight, the association became markedly stronger, with risk among women reporting the highest amount of vigorous activity decreasing by about 30% compared with women with no vigorous activity.
CB1 expression semi-quantified by Western blotting was significantly higher in preeclamptic placenta, and these findings were confirmed by immunohistochemistry. CB1 immunoreactivity was markedly stronger in syncytiotrophoblasts, the mesenchymal core, decidua, villous capillary endothelial and smooth muscle cells, as well as in the amnion in preeclamptic samples compared to normal pregnancies.
