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The Afghan government is now seeking to bring the Hezb-e-Islami to its side, a move that could "markedly" shift the balance of power in the battle against the Taliban.
This is in contrast to the large shifts in relative rank that would occur in a prioritization scheme reliant on singular pieces of information, wherein individual errors would markedly shift the relative ranks.
It therefore follows that if a mutation were to markedly shift the equilibrium toward the KS* state, it might allow the occupancy of this state even when the polyketide is tethered to the ACP from the same module.
In this regard, the addition of either PtdSer-displaying enveloped viruses (Bhattacharyya et al., 2013) or PtdSer-displaying apoptotic cells (Zagórska et al., 2014) has been found to markedly shift the dose response curves for Pros1 activation of Mer and Gas6 activation of Axl/Mer to lower ligand concentrations.
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In his latest show under the Gagosian Big Top, Mr. Serra adds some extra curves and corners, subtly but markedly shifting the tone and meaning of his work.
We found that the presence of the NHEJ mechanism markedly shifted the mutation spectrum from small deletions/insertions to large-scale deletions (from 2% to 24%).
Manure application significantly increased the diversity and abundance of ARGs in soil (P < 0.01), and also markedly shifted the bacterial composition that was significantly correlated with ARGs profiles.
Co-expression of SmCavβ markedly shifted the midpoint of steady-state inactivation in the hyperpolarizing direction.
In summary, combination treatment markedly shifted the tumour-associated myeloid population towards a more antitumour phenotype.
The cations Ni2+and Zn2+ markedly shifted the ΔErev to the left whereas Mn2+was less effective and Gd3+, Cd2+, Co2+ and Cu2+ were modest inhibitors (Fig. 10).
In contrast, incubation of hemoglobin with TD-1 markedly shifted the ODC to the left, reflecting a marked reduction of the P50 from 17 ± 0.3 to 4.2 ± 0.1 Torr (P < 0.001; Figure 2A).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com