Sentence examples for markedly sensitive from inspiring English sources

It has been reported that patients with some types of neuromuscular disorders are also markedly sensitive to muscle relaxants [6].

Experimental results indicate that: (1) WC Co cemented carbides are markedly sensitive to fatigue; and (2) their FCG rates exhibit an extremely large dependence on Kmax.

This finding indicates that high strength steels are markedly sensitive to pre-existent defects, such as burr, cracks at the cut edge or surface cracks, and they can be considered as low damage tolerant steels.

We refrained from stabilizing the CspB simply by solvent additives, because oligo-Ala induced fibril formation is markedly sensitive to changes in the composition of the solvent [36].

Foliation is markedly sensitive to the level of MDM2 as we found no overt abnormalities in Mdm2+/Δ7-9 cerebella in which the level of MDM2 is ∼50% of wild-type (data not shown).

Although PDK1 transgenic mice did not exhibit changes in mammary gland development, function and tumorigenicity, they were markedly sensitive to GW501516 treatment, where median tumor-free survival was reduced four-fold in comparison to a two-fold reduction in GW501516-treated wild-type mice.

Following pretreatment with IFN- γ, the cells became markedly less sensitive to UK-101, while their sensitivity to general proteasome inhibitors (epoxomicin and dihydroeponemycin) remained unchanged.

ICaL carried by α1c-D was markedly less sensitive to nitrendipine (IC50 17.1 μM) than α1c-wt (IC50 88 nM); a feature exploited to discriminate between engineered and native currents in transduced guinea-pig myocytes.

Likewise the CsAres culture proved markedly less sensitive to both DEB025 and CsA (EC50: 0.46±0.26 µM for DEB025 and 3.77±0.63 µM for CsA).

Thymus-derived Tregs are markedly less sensitive than effector T cells to oxidant stress induced cell death [36] and this perhaps suggests a particular role for ROS in Treg function and physiology.

The instrumental role of SphK1 inhibition in reduced cell growth was confirmed by cell viability assays, which showed that LNCaP overexpressing SphK1 were markedly less sensitive to the effects of androgen depletion (Fig. 3B).