6 A number of agents have US Food and Drug Administration marketing allowances as medical devices including GelClair, Episil, Mucotrol, Caphosol, and MuGard, but evaluation of medical devices is markedly less rigorous than is typical for biologics or drugs.
However, it is only since missing out on the Beijing Games that he has applied himself to a rigorous training regime and his times have improved markedly as a result.
Note that, although to two approaches are markedly different, the results were very similar and using this more rigorous approach did not changed the overall conclusions drawn.
There is massive evidence from individual smoker self-reporting that e-cigarettes enable users to quit smoking or to cut down markedly--a recent example is here--but few rigorous or realistic head-to-head comparisons with patches and gum.
[Page A21.] The United Nations secretary general, Kofi Annan, struck a markedly different tone, urging patience on the White House before it begins any military action if Iraq balks at the rigorous weapons inspections approved on Friday with a 15-to-0 vote in the Security Council.
The proportion of pupils getting at least grade C in English fell markedly on Thursday as 500,000 pupils received their results for the first time since Michael Gove overhauled GCSEs to make them more rigorous.
With more rigorous testing and penalties for performance-enhancing drug use a possible factor, the balance between bat and ball swung markedly in 2010, which became known as the "Year of the Pitcher".
72% of Americans still participate in some form of rigorous spring cleaning alongside a little less than half of Britons, and research indicates that these annual fits of cleanliness have a markedly positive effect.
A rigorous, objective analysis of potential locations, however, showed that a service center located in a city in China had a markedly higher net present value than one in India.
