markedly retarded

USAGE SUMMARY

The phrase "markedly retarded" is grammatically correct but may be considered outdated or offensive in contemporary usage.
It can be used in contexts discussing significant delays or impairments, particularly in developmental or cognitive terms, but caution is advised due to its potential to offend. Example: "The child's progress in learning was markedly retarded compared to his peers, prompting further evaluation."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

7 human-written examples

The drug release rate was markedly retarded in the increasing order of the amount of NC/TAβCD complex.

Journal of Controlled Release

Degradation was particularly rapid in tetrahydrofuran (THF) but was markedly retarded in presence of the radical scavenger 2,6-di-tert-butyl-4-methylphenol (BHT).

Polymer Degradation and Stability

Lysozyme-loaded PEG-PSMCU copolymers readily formed an in situ hydrogel after subcutaneous injection in SD rats, which markedly retarded the initial burst and led to the sustained release of lysozyme for 7 days.

Polymer

Thus, in the Diabetes Control and Complications Trial (DCCT), intensive insulin treatment, which achieved lower A1C than conventional treatment, also markedly retarded deterioration in C-peptide levels (2).

Diabetes Care

Importantly inhibition of miR-132 in the SVPs markedly retarded the therapeutic effect of stem cells thus confirming the importance of miR-132 in post-ischemic repair.

Cardiovascular Diabetology

However, although FA-disassembly rates in β3-WT NRP1Δcyto ECs were slightly reduced compared to their β3-WT counterparts, FA-disassembly rates were markedly retarded in β3-HET NRP1Δcyto ECs, illustrating the increased role for NRP1 in these cells.

DMM Disease Models and Mechanisms

Human-verified similar examples from authoritative sources

Similar Expressions

53 human-written examples

Opiates, although effective in reducing pain, have severe side effects (nausea, itching, reduced gut mobility, and urinary retention), which may markedly retard the postoperative recovery.

Acta Orthopaedica

Even though there is some embryo rescue by giving pregnant dams folic acid, RFC null neonates are markedly growth retarded and have multiple compromised organ systems [ 55].

Fluids and Barriers of the CNS

The hybrid photocatalyst markedly enhanced light absorption, significantly retarded charge pair recombination, facilitated interfacial electron transfer, and lowered interfacial charge transfer resistance.

Applied Catalysis B: Environmental

The progression resembles that found in homozygous lamin A knockout mice [ 19], which were indistinguishable from heterozygous or wild type at birth, but then showed severely retarded postnatal growth and markedly reduced life span.

Aging

In the other subregion, with higher values of φ2, the selectivity is significantly retarded to values which can be markedly below the lower asymptote.

Chemical Engineering Science

Expert writing Tips

Best practice

When using "markedly retarded", ensure the context is professional or scientific to avoid potential offense. Consider more neutral alternatives like "significantly delayed" in general communication.

Common error

Avoid using "markedly retarded" in casual or everyday conversation, as it can be perceived as insensitive or offensive. Opt for more neutral terms like "delayed" or "slowed" in non-scientific contexts.

Linguistic Context

The phrase "markedly retarded" functions as an adverb-adjective combination that modifies a noun, indicating a significant degree of delay or impediment. Ludwig provides examples where it describes processes or developments that are substantially slowed or hindered.

Expression frequency: Uncommon

Frequent in

Science

100%

News & Media

0%

Formal & Business

0%

Less common in

Academia

0%

Encyclopedias

0%

Wiki

0%

Ludwig's WRAP-UP

In summary, the phrase "markedly retarded" is grammatically correct and primarily functions to describe a significant delay or impediment, especially in scientific contexts. However, it's crucial to exercise caution when using this phrase, as it may be considered outdated or offensive in contemporary usage. As Ludwig indicates, more neutral alternatives like "significantly delayed" or "substantially impaired" are often preferable in broader communication. Given its formal and scientific register, it's best suited for technical writing and should be avoided in casual conversation to prevent potential misinterpretation or offense.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

significantly delayed

Replaces "markedly retarded" with a more neutral and commonly used expression to indicate a notable delay.

noticeably slowed

Indicates a clear reduction in speed or progress, similar to being retarded but with less intensity.

considerably hindered

Emphasizes the obstructive aspect of retardation, highlighting how something is being impeded.

distinctly impaired

Focuses on the diminished functionality or capability as a result of the retardation.

markedly slowed down

This alternative is slightly less formal and uses the phrasal verb "slowed down" instead of the single word "retarded".

substantially impeded

Uses stronger vocabulary to indicate a significant obstruction or prevention of progress.

clearly inhibited

Suggests that a process or function is being actively held back or restrained.

significantly suppressed

Indicates that something is being actively reduced or kept under control.

noticeably diminished

Highlights the reduced state or quality resulting from the retardation.

considerably lessened

Focuses on the reduction in intensity or amount due to the retardation.

FAQs

How can I use "markedly retarded" in a sentence?

You can use "markedly retarded" to describe a significant delay or slowing down of a process or development. For example, "The tumor growth was markedly retarded by the new treatment."

What are some alternatives to "markedly retarded"?

Some alternatives to "markedly retarded" include "significantly delayed", "noticeably slowed", or "considerably hindered".

In what contexts is it appropriate to use "markedly retarded"?

The phrase "markedly retarded" is most appropriate in scientific or technical contexts where precise language is required. It is less suitable for general conversation due to potential negative connotations.

Is "markedly retarded" considered offensive?

While grammatically correct, "markedly retarded" can be considered outdated and potentially offensive in certain contexts. Using more neutral alternatives such as "significantly delayed" is often preferable to avoid causing offense.