Sentence examples for markedly repressed from inspiring English sources

As expected, miR-124 markedly repressed the luciferase reporter activity in both cells (Fig. 5D,E).

Moreover, we found that abnormal elevation of extracellular glutamate (Glu) level induced by OGD was markedly repressed by hydroxy fasudil as measured by high performance liquid chromatography (HPLC).

Our results demonstrated that ABL SH3 mutant T79Y markedly repressed the expression of BCR-ABL signaling pathways in IM-resistant cell lines KCL22 and K562/G01 as well as IM-sensitive cell line K562.

qRT-PCR analysis showed that retroviral infection markedly repressed SALL4 expression in KG1a cells by 60%.

AR silencing in tumors strongly inhibited their growth, and importantly, also markedly repressed the VEGF production and angiogenesis.

It could be observed that the expression of SATB1 was markedly repressed in both mRNA and protein level (Fig. 4A).

Finally, reintroduction of p27Kip1 into p27Kip1-deficient T24T cells markedly represses the activation of JNK and c-Jun and reduces EGFR expression.

Interestingly, tumor suppressor genes such as DKK3 and gamma FBPα, the avian homolog of HIC-1 (hypermethylated in cancer 1), were repressed markedly by v-Src in CEF.

We observed that in all NS cell lines, the expression of the largely described stem markers CD133, Notch1, Nanog, Gli1, Sox2, Nestin, SonicHH, EZH2 and Olig1/Olig2, was markedly and significantly repressed after a 15-day forced differentiation.

A genome-wide integrated methylome-transcriptome analysis showed that LCP genes were markedly hypermethylated when repressed, and hypomethylated when active with a 40% difference in a broad region at the 5′ of the transcription start site (p < 10−87 for -6000 bp to -2000 bp, p < 10−73 for -2000 bp to +2000 bp, no difference in gene body p = 0.42).

Based on the metabolic gene expression profile, the effects of rapamycin, when given at a non-Akt suppressing dose, resembles that of HFD feeding in promoting energy storage at the expense of burning glucose (e.g., markedly elevated glucose kinase and repressed PEPCK expression, Figure 9).