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The cellular distribution of LmjKIN13-1 difroms from that of TbKIN13-1 in that its expression is markedly regulated during the cell cycle, probably by proteasomal degradation [23].
Taken together, the data indicate that Smyd1 and Smyd2 are the only Smyd-family members observed to be preferentially expressed in cardiomyocytes, and their levels are markedly regulated during cardiac development.
Apoptosis is not markedly regulated during mouse NS cell differentiation, and Bcl-2 expression is increased (data not shown).
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Bacterial microbes rather seem to use evasion strategies interfering with the expression of MAMPs, such as flagellin or T3S systems that are markedly down regulated during systemic infections (Broz & Monack, 2011).
Thus NRP-1 markedly regulates PDGFRα signalling when stimulated by these growth factors.
Sex steroid hormones markedly regulate the activity of immune cells, including lymphocytes, macrophages, granulocytes, and mast cells.
This suggests that these genes that are markedly induced during involution are not coordinately regulated during pregnancy or lactation.
However, how TAZ is regulated during differentiation remains unclear.
Meg9/Mirg expression is also regulated during embryogenesis.
PGAM2 is developmentally regulated during myogenesis.
First, KHC is temporally regulated during oogenesis.
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