Exact(1)
While this is a relatively short time window for treatments that require vigorous screening prior to instituting the treatment (e.g., tPA), a drug with a favorable safety profile can easily be administered in the field thus markedly reducing the time to treatment.
Similar(59)
RLX markedly reduced the time needed to complete skin normalization.
Wound closure in diabetic animals was observed at day 38±3 after the surgical procedure and RLX markedly reduced the time to complete wound closure.
Specifically, Van den Berghe et al. found that intensive insulin therapy (that is, administration of insulin to maintain blood glucose in the 80 to 110 mg/dl range) in ICU patients markedly reduced the time required to wean patients from mechanical ventilation, shortened ICU stay, and was associated with decreased incidence of ICUAW [ 9, 13].
Use of CS as the reference markedly reduced the times required for both the maximum-likelihood (5 vs 35 hr with bootstrapping) and Bayes MCMC (2 vs 22 hr) methods without a critical deterioration in tree topology when compared with whole genome alignment.
Markedly reducing the costs and time required for genome-wide discovery of cancer-specific mutations, such as with 'third-generation' instruments, will further open the door for individualised immunotherapy of cancer patients.
The development of automatically calculated BSI has markedly reduced the interpretation time and decreased inter-observer variability compared to visual analysis alone [2, 3].
In addition, the antioxidant activities of UAE were compared with those of conventional maceration and Soxhlet extraction methods, and the ultrasound-assisted extraction could give higher yield of antioxidants and markedly reduce the extraction time.
NHAG and indomethacin treatments markedly reduced the swing time on day 20 onward when compared to that of the arthritic control group (P < 0.05).
Further increase in exposure concentration markedly reduced the exposure time needed to reach a 50% reduction in the tidal volume (Fig. 1a).
Furthermore, in vivo time-lapse imaging of neurons in Xenopus brain revealed that NL1-induced filopodial stabilization was reversed by the application of AP5, which increased the elimination rate of preexisting filopodia by 77% and markedly reduced the life time of filopodia; this suggested that NL1-mediated filopodial stabilization requires NMDAR activity [ 58].
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Justyna Jupowicz-Kozak
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