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In summary, we observed a markedly reduced frequency of organ metastases in T3 colorectal cancers that exhibited either the MSI-H phenotype, a CLR or both.
The markedly reduced frequency of LCs in aged mice could be explained by either a decrease in the LC proliferation, increased LC apoptosis, or by a decrease in the number of LCs progenitors.
Fast-spiking interneurons are especially sensitive, with respiratory chain inhibition producing a markedly reduced frequency of inhibitory postsynaptic potentials, as well as decreased gamma power (Whittaker et al. 2011).
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Thereafter, both spontaneous Ca2+ release events were markedly reduced in frequency and field stimulation failed to elicit a response.
Interestingly, the pharmacologic and genetic approaches we conducted here to inhibit the M-CSF/PI3K/mTOR axis markedly reduced the frequency of GMPs in Sf bone marrow.
By contrast, application of an equimolar concentration of nonanoic acid markedly reduced the frequency of recurrent short discharges, and 4-methyloctanoic acid completely abolished the discharges 30 40 minutes after application.
The study shows that standard drug and the extract markedly reduced the frequency of faeces released from 100% (diarrheic rats) to 47.22 and 79.16 (125 mg/kg) to 48.61% (250 and 500 mg/kg) respectively.
Treatment with cimetidine markedly reduced the frequency of metastasis and significantly increased survival rate in the patients whose cancer cells expressed higher levels of the sLx and the sLa epitopes, but not in the patients whose cancer cells expressed none or lower levels of these epitopes, although such a cancer was considered to be less aggressive.
HRV-C-infected subjects showed markedly reduced detection frequencies of RSV and other respiratory viruses, providing evidence for a major interfering effect of HRV-C on susceptibility to other respiratory virus infections.
Reduced frequency of farmer poisoning.
The administration of diazepam (DZ) + pentobarbital (PB) 30 min after the beginning of the TsTx-induced SE was able to markedly reduce the frequency of the SRMSs and prevent the development of mossy fibres sprouting and hippocampal lesion.
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CEO of Professional Science Editing for Scientists @ prosciediting.com