Sentence examples for markedly prolonged the from inspiring English sources

RBC carrying suPAR circulated in rats similarly to naïve RBC and markedly prolonged the circulation time of suPAR.

Furthermore, knockdown of SPOP markedly prolonged the half-life of endogenous AR protein in LNCaP cells.

In bistris buffer, however, superoxide dimutase markedly prolonged the lag phase.

Starch promoted peripheral accumulation of the later infused Ringer´s acetate solution and markedly prolonged the elimination half-life.

Interestingly, reduction in temperature markedly prolonged the TCR, whereas the dependence of TCR on [Ca2+]o remained minimal.

The investigators found that pharyngeal oxygenation markedly prolonged the time to severe systemic arterial oxygen desaturation, defined as oxygen saturation (SpO2) of less than 60%.

Despite the use of QT-prolonging antiemetics, treatment with romidepsin did not markedly prolong the QTc interval through 24 h.

In this study, we have shown that abrogation of dNTP biosynthesis, which is caused by csn1Δ, ddb1Δ or cdc22-M45 mutatiors or HU treatment, markedly prolongs the duration of horsetail nuclear movements and that this prolongation results from activation of the Cds1-dependent DNA replication checkpoint.

Hypokalemia would be predicted to further reduce the current density of IKr channels already impaired at baseline by the P1086fs+32X mutation in our patient, thereby markedly prolonging the QT interval and increasing the risk of torsade arrest in our proband.

Recently, CDs have garnered much interest because of their ability to clear stored cholesterol from Niemann Pick Type C (NPC) cells and markedly prolong the life of NPC1 disease mice.

To test this idea, we used the K+ channel blocker tetraethylammonium (TEA), which markedly prolongs the β cell action potential (Atwater et al., 1979).