Only rarely does chest pain coincide with hypertensive peristalsis, particularly if the contractions are markedly prolonged.
RBC carrying suPAR circulated in rats similarly to naïve RBC and markedly prolonged the circulation time of suPAR.
The E6-GALNS tagged enzyme had markedly prolonged clearance from circulation, giving over 20 times exposure time in blood, compared to untagged enzyme.
What's more, the antiwear lifetime is markedly prolonged to ∼8 h under a high applied load of 2 N, which is over seven times longer than that of GO films.
Immediately after weaning, the transit was markedly prolonged but shortened with increased postweaning time (3 days, 2 and 3 weeks postweaning, 85% excretion in 175.5, 77, and 50.5 h, respectively).
A recent and surprising finding for the PTHR1 is that it can form highly stable complexes with certain PTH ligand analogs and thereby mediate markedly prolonged signaling responses in cells and in animals.
Covering the surgery site by drug-loaded AMPN mat after tumor resection, in both subcutaneous and orthotopic HCC model in mice, the recurrence of HCC was significantly retarded and the survival time of mice was markedly prolonged.
The modified CRAd-Cans manifested the same selective replication and cytocidal effects in pancreatic cancer cells as ONYX-015 in vitro, yet showed greater reduction of tumor growth in nude mice with markedly prolonged survival rate in vivo (P < 0.05), compared to that of either ONYX-015 or Ad5-Cans.
The microstructured catalyst obtained with a high SG amount of 50% contains a smaller crystal size of ∼70 nm and higher mesopore volume of 0.21 cm3 gzeolite−1, which markedly prolonged single-run lifetime with a remarkable decrease in the coking rate in the MTP process.
Neither total lymphoid irradiation nor cyclosporine alone markedly prolonged graft survival.
After being coated with polyethylene glycol (PEG) or dendrimers, blood circulation time was markedly prolonged, and improved biocompatibility was achieved [9 11].
