Sentence examples for markedly prolong from inspiring English sources

Despite the use of QT-prolonging antiemetics, treatment with romidepsin did not markedly prolong the QTc interval through 24 h.

Recently, CDs have garnered much interest because of their ability to clear stored cholesterol from Niemann Pick Type C (NPC) cells and markedly prolong the life of NPC1 disease mice.

Taken together, NSCLC tumour vaccines markedly prolong median OS (p<0.00001), median TTP (p=0.001) and median PFS (p=0.005), improve clinical response rate (p=0.05) and lessen adverse side effects (p<0.00001).

In this study, we have shown that abrogation of dNTP biosynthesis, which is caused by csn1Δ, ddb1Δ or cdc22-M45 mutatiors or HU treatment, markedly prolongs the duration of horsetail nuclear movements and that this prolongation results from activation of the Cds1-dependent DNA replication checkpoint.

Only rarely does chest pain coincide with hypertensive peristalsis, particularly if the contractions are markedly prolonged.

RBC carrying suPAR circulated in rats similarly to naïve RBC and markedly prolonged the circulation time of suPAR.

The E6-GALNS tagged enzyme had markedly prolonged clearance from circulation, giving over 20 times exposure time in blood, compared to untagged enzyme.

What's more, the antiwear lifetime is markedly prolonged to ∼8 h under a high applied load of 2 N, which is over seven times longer than that of GO films.

Immediately after weaning, the transit was markedly prolonged but shortened with increased postweaning time (3 days, 2 and 3 weeks postweaning, 85% excretion in 175.5, 77, and 50.5 h, respectively).

A recent and surprising finding for the PTHR1 is that it can form highly stable complexes with certain PTH ligand analogs and thereby mediate markedly prolonged signaling responses in cells and in animals.

Covering the surgery site by drug-loaded AMPN mat after tumor resection, in both subcutaneous and orthotopic HCC model in mice, the recurrence of HCC was significantly retarded and the survival time of mice was markedly prolonged.