Sentence examples for markedly modulated in from inspiring English sources
Based on our previous work [33], our current study demonstrated that multiple function-related genes have been markedly modulated in CD4+CD62L+ Tregs after coculture with CB-SC.
We also identified several genes that were markedly modulated in MCF-7 cells treated with rapamycin plus CN-A.
Although the expressions of p53, p21Cip1, p27Kip1 and cyclin D1 mRNAs did not significantly change, we found that expressions of several genes such as cyclin G2, TGFBI, BIK, GRB7 and ERG3 were markedly modulated in MCF-7 cells treated with rapamycin plus CN-A.
Such ECM proteins include fibronectin, laminin, collagen I (COL1), collagen IV (COL4) and collagen VI (COL6) and these ECM components are markedly modulated in response to chemotherapy (Dangi-Garimella et al, 2011; Sherman-Baust et al, 2003; Su et al, 2007).
Altered expression of FUT4, FUT6 or FUT8 markedly modulated the activity of the PI3K/Akt pathway in human HCC cell lines.
Furthermore, the PPI and social interaction deficits noted in the Bdr mutants were markedly modulated by PNS.
In addition, regulating FUT4, FUT6 or FUT8 expression markedly modulated the activity of the phosphoinositide 3 kinase (PI3K /Akt signaling pathway and MDR-related protein 1 (MRP1) expression.
In contrast, progression of this devastating form of carcinogenesis is markedly modulated by the inflammatory microenvironment.
We consider that these subtle phenotypes could be important and markedly modulated by genetic background and environment (Wood, 2000), or under conditions that were not tested in the current study.
In this study we examined the effects of various binary mixtures consisting of a DNA-reactive procarcinogen (B[ a]P or PhIP) and hormone-like agent (E2 or lindane) to determine whether such in vitro exposures might markedly modulate genotoxicity and/or survival in damaged cells.
Additionally, we demonstrate that epigenetic modulating drugs (TSA, 5-Aza) do not markedly modulate the expression Notch-1 or Jagged-1 in UV-B-treated human keratinocytes in vitro.
