Sentence examples for markedly limit from inspiring English sources

Taken together, these failings markedly limit the utilization of the Vienna classification of Crohn's disease in clinical trails or disease management.

However, the best approach for combining topotecan with other anticancer agents has been debated because additive myelosuppresssion can markedly limit the doses of drugs that can be safely administered together (Cannistra, 1999).

We have included this point in our Results section and noted that it supports the reviewer's conclusion that other factors, most likely protein-protein interactions, markedly limit LIMK1 diffusion in spines.

As shown in Table 1, persistent cross-protection above 70% would be necessary to markedly limit the size of a second pandemic season due to a virus with different antigenic properties.

We have modified both our Results and Discussion to include these points and note that they all support the reviewer's hypothesis that LIMK1 does not behave like a soluble protein and that other factors, most likely protein-protein interactions, markedly limit LIMK1 diffusion in spines.

For his study, Wernig selected patients who had severe but not total cord damage: their ability to move was markedly limited but they were not completely paralyzed.

He introduced a moderate constitution that left much power in the hands of the nobles but markedly limited the absolute powers of the throne.

However, due to the delicate nature of the fruit, poor handling practices and inadequate storage facilities, the shelf life of the Chinese bayberry is still short, which markedly limits its market.

A poor occurred if the patient had markedly limited activity regardless of the presence of other criteria, any patient with significant pain (requiring narcotics) or a patient with three of the other criteria.

The resultant combination of systemic hypotension and vasoplegia blunts the normal redistribution of blood flow usually seen in circulatory shock and markedly limits the host's ability to sustain the vital organ blood flow.

In contrast to the genetic simplicity of STS in the first group, the biological and molecular diversity of complex karyotype STS markedly limits the identification of single and specific "oncogenic addiction" aberrations.