Exact(5)
Externalists, for example, may invite us to consider cases in which a person judges it right to φ, while believing it would in fact be impossible to succeed in doing φ, or cases in which she thinks doing φ would markedly interfere with her welfare or would prevent her from obtaining something she dearly desires.
The presence of VEGF in samples, at expected physiological concentrations, did not markedly interfere in the quantification of bevacizumab.
NDGA treatment of SW 850 cells also did not markedly interfere with further phosphorylation of p70s6k in response to TGFα.
Moreover, many of the identified Gordon's disease-causing mutations (Q309R, R384Q, L387P, S410L, S432N, R528H, R528C and N529K) located within the putative substrate-binding Kelch-like domain of KLHL3 markedly interfere with binding to WNK1.
In contrast, a heparin concentration of 10 μg/ml did not markedly interfere with cAMP-dependent phosphorylation of the AMA1 CPD (Supplementary Figure S1 at http://www.biochemj.org/bj/452/bj4520457add.htm).htm
Similar(55)
This transformation would be inhibited by traces of silicate, aluminate and stannate [32], and markedly interfered by Ti(IV), Cu II), Cr III) and Ni II), and the coexistence of Fe(II) and SO 4 2- is necessary for this transformation [31].
However, the deletion mutants were relatively resistant to the aminoglycoside antibiotic neomycin, which alters miscoding (Figure S2B), whereas other aminoglycosides, i.e. gentamycin and spectinomycin, known to impair translocation and accuracy of tRNA ejection during proof-reading [27], markedly interfered with the growth of the deletion strains (Figure 4D).
The derivatization process markedly interfered with the subsequent staining of the proteins with SYPRO Rose on either type of membrane.
We found that knockdown of FAK markedly interfered with normal vascular morphogenesis in this assay, leading to a nearly complete loss of cells by day 14 (Fig. 8A).
This large increase in polymorphism with increase in host mutation rate markedly interferes with clearance of maladapted alleles in clonal populations.
Similar to the results obtained with leukemic cells, the expression of HDAC7 in Namalwa cells markedly interfered with the growth of lymphomas.
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