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The expression of CHOP is low under non-stressed conditions, but its expression markedly increases in response to ERS through IRE1-, PERK- and ATF6-dependent transcriptional induction.
Correspondingly, the dielectric relaxation observed in Sr1−xMnxTiO3 markedly increases in intensity and slightly shifts towards a higher temperature for ceramics sintered in nitrogen compared with those fired in air or oxygen.
The present work confirms that circulating IL-6 markedly increases in the C26 hosts, yet PD administration does not prevent this increase (Fig. S3).
Apelin regulates body fluid homeostasis and cardiovascular functions through the apelin receptor, APJ, and the level of plasma apelin markedly increases in obesity that is associated with insulin resistance and hyperinsulinemia [11] [14].
Furthermore, after the inhibition of lysosomal proteolysis, the abundance of LC3-II markedly increases in the uninfected cells.
Interestingly, the corresponding human genomic position (the e239-e240 intron in ENST00000589042) represents the exact transition point for where disease severity markedly increases in DCM TTN truncation patients.
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Protein levels of NF-κB p65 were markedly increased in the myocardium of db/db mice.
Significantly, such aggressive variants markedly increase in castration-resistant PCa (CRPC) patients41.
Linoleic acid levels were markedly increased in DIO rats compared to DR rats irrespective of diet and duration (Fig. 5b).
We previously reported that the gastric ulcerogenic response to NSAIDs was markedly increased in arthritic rats.
Conclusion: Levels of rHcy and other aminothiols are markedly increased in patients with impaired renal function.
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