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The scintigraphic images showed a single increased focus of 99mTc activity in the neck with a markedly increased uptake at the injection site (Figures 3 and 4).
Interestingly, the core of the infarct manifested markedly increased uptake, exemplified by a brighter staining (yellow arrow), as compared to the more peripheral regions (red arrowheads).
When R9 was added to either rGel alone or the CPE-G4S-rGel fusion protein it markedly increased uptake and cytotoxicity.
A pilot study in Scotland has already shown that FIT improves uptake (Steele et al, 2013) and a pilot using FIT that commenced in England in April 2014 is also demonstrating markedly increased uptake from current gFOBt (BCSP Southern Hub report).
Patients were classified based on the best tumor response according to the Lugano classification, 4 which is visual five-point scale designed to reduce interobserver variability as: 1, no uptake; 2, uptake ≤mediastinum blood pool; 3, uptake ≤liver; 4, moderately increased uptake >liver; or 5, markedly increased uptake >liver and/or new lesions.
The visual response criteria used the Deauville five-point scale (5-PS): 1, no uptake; 2, uptake ≤ mediastinum; 3, uptake > mediastinum but ≤liver; 4, uptake moderately increased compared to the liver uptake at any site; and 5, markedly increased uptake compared to the liver at any site and new sites and/or new sites of disease.
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In contrast, markedly increased FDG uptake is seen in proliferative neoplastic disorders that often corresponds with a localized mass [32].
In 42 patients Ga SPECT/CT showed markedly increased bone uptake, consistent with a diagnosis of osteomyelitis.
In a case report, a patient with MF was reported to show a markedly increased FDG uptake throughout the spleen and liver.
Examples include increased staff satisfaction, increased uptake of flexible working or training and increased knowledge of Athena Swan principles.
Writing to the Clean Energy Finance Corporation to ensure "significantly increased uptake of large-scale solar and energy efficiency".
More suggestions(15)
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