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This bridge restricts the flexibility of the ribofuranose ring and locks the structure into a rigid C3-endo conformation, conferring enhanced hybridization performance and markedly increased stability.
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A designed mutant of a spider silk protein domain, NT*, is unable to dimerize and displays markedly increased solubility, stability and refolding capacity compared to NTwt.
The presence of cylindrical microdomains of either the poly isoprene-LC) or poly isoprene-LCork markedly increased the thermal stability of the LC.
Zinc binding, disulfide bond formation, and dimerization limit the flexibility of the Zn-loop and markedly increase protein stability (Furukawa and O'Halloran, 2005).
Here we have shown that zeolites with extra-large pores can be prepared Ge-free, thus markedly increasing their stability toward water, and therefore opening up potentially new applications for zeolite materials with large pores.
FLAG Rev-erbα has a short halFLAG Rev-erbαroximately 30 min, but co-expression withasBC1 markedly increashortev-erbα protein stability and half-life tofapproximately 1.5 h.
Furthermore, although complexation efficacies of siRNAs are not altered, complex stabilities are markedly increased in OM-PEI complexes.
At the same time the catalyst stability has also been markedly increased by alleviating the sulfur loss and by stabilizing ZrO2 tetragonal crystalline structure.
Conclusions: The stability of BNP was markedly increased in the presence of kallikrein-specific PPACK II and a broad spectrum of serine PIs.
The kinetic stability of graphite intercalation compounds (GICs) is markedly increased by a surface passivation reaction that occurs under strong reducing conditions in the presence of long-chain tetra-n-alkylammonium cations.
In contrast, both LND cells demonstrate markedly increased levels of processed NTF and CTF, indicating a markedly increased level of PS-1 proteolytic processing or proteolytic fragment stability compared with WT cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com