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When serum ALT in H1R−/−/H2R−/− mice was measured as a marker indicative of liver damage, the markedly increased level after sepsis was subsided (Fig. 8c).
Freshly isolated human PBMCs treated with the starvation medium EBSS (Earle's Balanced Salt Solution) showed a markedly increased level of LC3-II compared to RPMI controls.
In contrast, both LND cells demonstrate markedly increased levels of processed NTF and CTF, indicating a markedly increased level of PS-1 proteolytic processing or proteolytic fragment stability compared with WT cells.
We found that MUC4 markedly increased level of phosphorylated Bad in CD18/HPAF/Scr cells.
Electroporation of the miR-26a inhibitor into cultured sensory neurons led to markedly increased level of GSK3 β.
However, the detection of a markedly increased level of IL-6 in pleural fluid argues against a diagnosis of adenocarcinoma.
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Despite immunosuppressive therapy, markedly increased levels of several pro-inflammatory cytokines were produced in WB cultures from the patient.
In addition, hyperosmolarity treatment (in the absence of AcD treatment) markedly increased levels of SPAK mRNA transcripts.
In the EDL there were markedly increased levels of MAFbx/atrogin-1 and MuRF1 mRNA within 6 h after the onset of LPS infusion (Fig. 3A & 3B respectively).
Immunoblotting results also showed that U18666A treatment markedly increased levels of Mdm2 phosphorylated at Ser166 (referred to as p-Mdm2 hereafter; Fig. 3A).
It was apparent that cells seeded on tri-component scaffolds showed markedly increased levels of pFAK, as well as greater cell spreading, as compared with PCL or PCL/HA (Figure 5).
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