Sentence examples for markedly increased activity from inspiring English sources

In addition, IL-4 markedly increased activity of caspase-3, and inhibition of this enzyme suppressed IL-4-induced apoptosis in a dose-dependent manner.

In particular, the highest dose (3 mg/kg), which decreased lever pressing, markedly increased activity during testing.

Cells from these mice showed reduced PARG activity in the nuclei, but markedly increased activity in the mitochondrial fraction.

On the contrary, the ΔKDEL transfectants exhibited markedly increased activity and secretion of MMP-2).

Consequently, newer fluoroquinolones such as gemifloxacin (60 ) and others now under development have markedly increased activity compared with traditional agents.

Results of the present study show that treatment with both coplanar and non-coplanar PCBs markedly increased activity of NOX.

SKF81297 markedly increased locomotor activity in the activity boxes (Fig. 5).

Ferrous and stannous ions markedly increased the activity of molybdenum-reducing activity in this bacterium.

We also observe markedly increased WNK1/WNK3 activity in the cells lacking SPAK/OSR1 activity, indicating these STE20 kinases suppresses WNK isoform activity either via a negative feedback loop or indirectly through inhibition of NKCC1 activity, resulting in cells becoming osmotically stressed.

SH-SY5Y cells transfected with the pEGFP-C3 control vector or left untransfected had similar puromycin-sensitive activity, whereas the expression of GFP-PSA markedly increased this activity (Fig. 4A).

In a seminal study to determine the structural basis for lipid activation of PKN1 activity, Yoshinaga et al. [ 15] made a series of truncation mutants and found that while full-length PKN1 displayed low basal activity and demonstrated a dependence on arachidonic acid, N-terminal truncation at residue 511 markedly increased specific activity and decreased arachidonic acid sensitivity.