Sentence examples for markedly higher levels of from inspiring English sources

p21 expression in isogenic cell lines directly correlated with markedly higher levels of MGMT mRNA, protein, activity and greater resistance to alkylating agents.

Further, vaults induced markedly higher levels of IFNγ, necessary for eradication of chlamydiae, soon after infection in target tissue.

Indeed, we have demonstrated that circulating pDC of HIV-1 patients express markedly higher levels of IFNα mRNA and protein [28].

Two of these SNPs showed markedly higher levels of significance for association with LDL-C than the surrounding SNPs: rs6511720 (predicted p-value = 4.6×10−6) and rs2228671 (predicted p-value = 2.4×10−6).

Furthermore, we observed that individuals carried the XRCC1-194 T allele or XRCC1-399 AA homozygotes displayed markedly higher levels of PAH-DNA adducts, compared with the wild-type homozygote.

Circulating plasmacytoid dendritic cells (pDC) decline during HIV-1 infection, but at the same time they express markedly higher levels of interferon alpha (IFNα), which is associated with HIV-1 disease progression.

Compared to Cabernet Sauvignon, Shiraz had higher levels of astilbin (3-fold) and hydroxybenzoate (1.7 - 3-fold), whereas Cabernet Sauvignon sap was characterized by a markedly higher level of epigallocatechin (6.3-fold) than Shiraz.

Treatment of macrophages with LPS, which is a ligand of Toll-like receptor 4, or with type 1 interferon greatly increases expression of cholesterol 25-hydroxylase, resulting in a markedly higher level of oxysterol in the blood 44, 45.

The asymptomatic ratio among schoolchildren in Taipei City, the only urban city in our study with markedly higher level of education among parents compared to other rural areas, is significantly smaller than that of the other rural locations.

Our results showed that there was no difference in Rankl expression; however, Nur77 KO osteocytes express a markedly higher level of Opg, leading to a significantly lower Rankl/ Opg ratio.

Second, there was a markedly lower level of HDLC in Desert subjects and a markedly higher level of HDLC in Turpan subjects, resulting in significantly different patterns of the TC:HDLC ratio, which is commonly used as a predictor of cardiovascular incidents and death, 16 17 suggesting different possibilities for the role of HDLC in the elevated risk of CVD in the two subgroups.