Sentence examples for markedly higher level from inspiring English sources

So with your first big year, be careful that you don't reset your expectations to a markedly higher level and then years later realize you're in trouble.

Meanwhile, domestic club competitions across Asia and Oceania have been weakened by the need for top national players to join better clubs in Europe or South America to test and improve their talents at a markedly higher level.

The intracellular calcium fluctuates at a markedly higher level when receptor trafficking is allowed in the model.

It was of markedly higher level in the model group mice (12.1 ± 0.6 nmol/mg protein, P < 0.01).

A negative trend for gentamicin resistance was also observed for S. epidermidis, although at a markedly higher level.

Treatment of macrophages with LPS, which is a ligand of Toll-like receptor 4, or with type 1 interferon greatly increases expression of cholesterol 25-hydroxylase, resulting in a markedly higher level of oxysterol in the blood 44, 45.

p21 expression in isogenic cell lines directly correlated with markedly higher levels of MGMT mRNA, protein, activity and greater resistance to alkylating agents.

Further, vaults induced markedly higher levels of IFNγ, necessary for eradication of chlamydiae, soon after infection in target tissue.

Indeed, we have demonstrated that circulating pDC of HIV-1 patients express markedly higher levels of IFNα mRNA and protein [28].

Furthermore, we observed that individuals carried the XRCC1-194 T allele or XRCC1-399 AA homozygotes displayed markedly higher levels of PAH-DNA adducts, compared with the wild-type homozygote.

Two of these SNPs showed markedly higher levels of significance for association with LDL-C than the surrounding SNPs: rs6511720 (predicted p-value = 4.6×10−6) and rs2228671 (predicted p-value = 2.4×10−6).