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The results in this study show that the rest and activity cycle of Bdr mice is phase advanced and markedly fragmented under a 12 12 LD cycle.
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Mr Cameron and his wife Samantha are hosting an exemplary party in Downing Street, having applied to close their already inaccessible road.Yet since William's parents, Charles and Diana, married in 1981, the country's streets have become markedly more fragmented.
Electron microscopy showed markedly swollen mitochondria with fragmented cristae.
MNs with pyknotic nuclei, or with a markedly atrophic, irregular or fragmented soma were not counted as alive.
Intriguingly, mitochondria of Mfn2-deficient neurons were markedly enlarged, and not fragmented as would be anticipated if Mfn2 deletion had prompted a mitochondrial fusion defect.
Upon treatment of cells with 25 μ M NDGA for 12 h, the proportion of cells exhibiting fragmented DNA markedly increased from 2 to 34% in SW 850 and from 0to26%6% in C4-I cells.
Entrepreneurship research has evolved markedly over the past three decades and has grown from an embryonic and fragmented state (Shane and Venkataraman 2000; Busenitz et al. 2003; Zahra 2005; Schildt et al. 2006), with its legitimacy being questioned (Low and MacMillan, 1988), to a maturing field of study (Meyer et al. 2012; Busenitz et al. 2014; van Burg and Romme 2014).
Thus, our observation that isolated mitochondria exhibited markedly enhanced sensitivity to mPTP opening could be a direct consequence of the fragmented mitochondrial morphology we observed, although it is important to note that we have no basis for comparing the degree of fragmentation in the isolates we studied to that seen in mitochondria undergoing fission in vivo.
However, the middle class has grown markedly since the mid-20th century, and the nation's economic and social oligarchy has become somewhat fragmented as newly affluent families have joined its ranks.
I feel less fragmented.
It is also more fragmented.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com