Sentence examples for markedly extend from inspiring English sources

NSCs engineered with a wide array of cytotoxic agents have been found to significantly reduce tumor volumes and markedly extend survival in preclinical models.

These findings markedly extend previous investigations of CYP19A1 and cardiovascular disease.

Although some of these complications seem to be minor, they can markedly extend the postoperative length of stay and treatment cost and should not be ignored.

Hence, their possible fossil occurrence in Antarctic freshwater ecoystems of the early Eocene greenhouse world would markedly extend their palaeobiogeographic distribution, indicating that their evolutionary history may be more complex than currently recognized.

Successive improvements have markedly extended the analytical capability of the set-up.

These results indicate that the basal plane strength of HOPG is higher, and that fine local destruction does not easily occur until the deformation range is markedly extended.

Researchers have shown that a class of antiseizure drugs markedly extends the life span of the roundworm Caenorhabditis elegans a finding that may have implications for higher organisms.

We further demonstrate that the LbL nanoarchitecture significantly reduces the elimination rates of both drugs tested and markedly extends their systemic circulation times, paving the way for efficacious tumor drug delivery.

As expected, LFA-1 engagement (adhesion to rICAM-1) markedly extends the half-life of IFN-γ and TNF-α mRNA in MKK3+/+ (wt) T cells (Fig. 6B).

The TOY3-treated mice had a markedly extended lifespan compared to Fc-treated mice (50% survival: ∼60 hr versus ∼26 hr, P<0.001), and the 40% of TOY3-treated mice were completely rescued to live (Figure 6E).

Since the first report by McCay et al that restricting food intake of rats markedly extended their mean and maximal lifespan [1] CR has been proven to be a robust feeding regime for lifespan extension in a wide range of model organisms including yeast, invertebrate animals and many mammalian species [2].