Sentence examples for markedly elevated expression from inspiring English sources

Among these, vascular endothelial growth factor (VEGF) is important in many tumour types due to both its potent activity and markedly elevated expression level.

Markedly elevated expression levels of IL-17), RORc), and MMP-3) mRNA were found in RASFs after stimulation with IL-6, which were significantly suppressed by T-614 or MTX in RASFs.

The markedly elevated expression of FcγRI/CD64 among SLE patients with LN may serve as a surrogate marker of renal disease that correlates with both established measures of renal dysfunction (increased serum creatinine, blood urea nitrogen, and proteinuria) and inflammation (elevated serum CRP, C3 deficiency).

In comparison to IECs isolated from control mice and those colonized with E. coli MG1655, IECs from EcN treated animals showed a markedly elevated expression of ZO-1 protein (Figure 3B).

As detailed in Table 4, the chromosomally-borne variant of SLS65 led to markedly elevated expression of the PlevD-cat promoter fusion in cells growing in glucose or galactose, whereas expression in fructose or mannose was slightly lower than in the wild-type background.

Several of these zebrafish CYPs exhibited markedly elevated expression levels at some time during development, but a large number, including more than three-quarters of the total genomic complement, showed distinct temporal expression patterns.

Skin biopsies from patients with scleroderma were characterized by markedly elevated Nab2 expression, localized primarily in the nuclei of epidermal keratinocytes and cells lining dermal appendages.

In particular, the markedly elevated RTL1 expression primarily causes the KOS14 phenotype [ 14, 15].

Depletion of p27Kip1 in cells markedly elevated EGFR expression through transcriptional repression of Egfr by p27Kip1 via the JNK/c-Jun cascade.

Also, Liu and his colleagues reported that markedly elevated protein expression of IL-13 was detected in patients with HCV-associated cirrhosis which could elucidate the elevated P-selectins in patients with HCV [ 54].

Data showed that knockdown of CLIC4 markedly elevated the expression level of CHOP and active caspase 4 in HN4 cells compared with the scrambled siRNA group regardless of the presence of ATP (Fig.  6).