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Heparanase levels in the urine of T2DM patients were markedly elevated compared to healthy controls (1162±181 vs. 156±29.6 pg/ml for T2DM and healthy controls, respectively; Table 2, Fig. 1A), increase that is statistically highly significance (P<0.0001).
By contrast, CD248 staining throughout the synovium of inflamed K/BxN joints was markedly elevated compared to non-inflamed controls.
Hence, the ratio of sympathetic to parasympathetic inotropic responses was also markedly elevated compared with controls (P <.001),.
Absolute values of these biomarkers in these children were markedly elevated compared with non-tropical reference values in nearly all cases.
It is worth noting that in MCF-7 2A MCF-7 2Adogenous levels of Bcellsand phosphorylatendogenousere markedlevelsvated cofpared to parental MCF-7 cells.
The plasma level of BH4 in septic patients was indeed markedly elevated compared with that in volunteers (140.0 ± 148.1 vs 24.1 ± 4.8 pmol/ml, P < 0.01).
Similar(34)
Of note, although injury score was markedly improved by CORM-2 treatment, it was still elevated compared to sham-operated rats.
Instillation of bleomycin markedly elevated RVSP compared with saline-treated controls (32.0 ± 5.9 mmHg vs. 21.2 ± 5.9 mmHg; P < 0.05).
However, irrespectively of the causes, the fact remains that the levels of FA in pond populations are markedly elevated as compared to marine populations.
When subjects were divided into tertiles based on FSTL3 levels, women with the lowest levels demonstrated a markedly elevated risk compared with women with the highest levels.
Although the frequency of the TGFBR1*6A allele was similar in non-HNPCC familial cases and controls (0.084 and 0.106, respectively; P=0.23), the frequency in HNPCC cases was markedly elevated (0.157 P=0.0455) compared with the controls.
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