Sentence examples for markedly disrupted from inspiring English sources
Rome, Italy September 4, 422 Rome, Italy Saint Boniface I, (born, Rome died Sept. 4, 422, Rome; feast day September 4) pope from 418 to 422, whose reign was markedly disrupted by the faction of the antipope Eulalius.
Results showed that gill tissue architecture was markedly disrupted.
Moreover, the learning and memory in offspring (PD21, PD60) were markedly disrupted.
REM sleep, also known as paradoxical sleep, is markedly disrupted or diminished in patients with OSAS.
Administration of CCl4 markedly disrupted the normal architecture of the kidney cell by degenerating the tubules and collapsing the glomerulus (Fig. 4b).
Moreover, our work revealed that the binding of BAHBAHD1 to H3K27me3 was markedly disrupted by adjacent H3S28 phosphorylation a hallmark of the transcriptional response to stress signaling (Sawicka, Hartl et al. 2014).
Recent work showed that myosin II and cytosolic CKs are highly enriched at the apical adherens junction of polarized intestinal epithelial cells, and pharmacological inhibition of CK markedly disrupts apical junction assembly and barrier integrity.
The mutations in the RUNX3 motifs have been shown to markedly disrupt promoter activity, suggesting a role for RUNX3 in activation of the human L1 expression.
Consistent with this assumption, previous studies of human L1 promoters also identified the YY1-binding site as an important sequence for L1 expression and found that mutations in the putative YY1 motif markedly disrupt promoter activity [11], indicating that functionally intact YY1 motifs are required for transcriptional initiation of human L1 elements.
OA markedly disrupts hemicellulose and simultaneously re-localizes lignin moieties, aiding the increased exposure of cellulose to cellulases [ 29, 30].
Furthermore, EspH markedly disrupts actin cytoskeleton structure and induces cell rounding up when ectopically expressed or delivered into HeLa cells by the bacterial T3SS.
