Indeed, the comparative studies on HUVECs and HMEC-1 cells showed that they may markedly differ with respect to various features associated with their angiogenic potential, including the basal proliferative capacity, magnitude of the angiogenic factor release, secretion of VEGFR-1, and response to exogenous growth factors [ 32].
We derived a lineage of cell lines with markedly differing susceptibilities, unexplained by PrPC expression differences, to identify such factors.
We describe here multicolor flow cytometry analyses combining detailed phenotypic and functional characterization of total as well as memory subsets of CD4+ and CD8+ T cells from SHIV-infected rhesus macaques with no clinical symptoms but exhibiting markedly differing viral loads associated with differential cytokine production in response to non-specific in vitro stimulation with PMA+I.
We chose to use two different population sources, African American and Hispanic American, with markedly differing degrees of global African ancestry admixture (Bedoya et al. 2006; Behar et al. 2010), rather than two different collections from the same population, in order to test whether associations were robust to differing global background genomic composition.
In line with the idea that selection from the initial pool under Th polarizing conditions acts through selection of clones with differing avidities, Th1 and Th2 lines developed with markedly differing profiles of co-stimulatory molecule expression.
We present two cases of CST with markedly differing clinical presentations, medical comorbidities, and degree of impairment.
These figures powerfully illustrate that a common metabolic response underlies the perception of the drugs in independent AML cell lines with markedly differing constitutive metabolomes.
In European countries, there is no single payment plan available and each health care system functioning as a separate entity, often with markedly differing regulations.
These data establish that the disparity in viability following exposure to aspirin in CRC lines compared to lines derived from other cancer types is associated with markedly differing responses of the NF κB pathway to aspirin.
As we observed, jcBNST neurons classified as type I, II or III cells and displaying clear differences in their voltage output under DC stimulation, do not markedly differ when stimulated with stochastic inputs via dynamic clamp.
