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On the other hand, G-quadruplex-forming sequences that favor an all-parallel propeller fold are now predicted to be markedly destabilized if thymine photodimers are formed in their loop regions.
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However, we found that the kinase activity of LRRK2 is important for stabilizing cellular levels of LRRK2 because an artificial variant of LRRK2 lacking kinase activity was markedly and consistently destabilized even in the absence of exogenous CHIP (Figure 3C).
The region is destabilized".
Societies will be destabilized.
The meanings of garments were seriously destabilized.
This is exactly how markets become destabilized.
And it has profoundly destabilized the Middle East.
Trump's outburst destabilized the negotiations.
Constable was feeling destabilized and depressed.
Nor has the political system been destabilized.
The characters are so frightened, so destabilized.
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