Markedly hypoechoic was defined as lower echogenicity than the adjacent strap muscles.
The tumors in control animals were grossly hemorrhagic and on light microscopy, displayed infiltration of tumor cell masses by a network of markedly dilated, poorly defined, anastomosing vascular spaces filled with extravasated RBCs (Fig. 3A; Fig. S3).
Similarly, multivariate Cox regression analysis suggested that risk of death was markedly reduced in patients defined as race 'other' compared with the rest of the population (HR=0.64).
Radical surgery would have deteriorated the quality of life of our patient markedly as this was defined by freedom from dialysis as stated repeatedly by her.
On ultrasound (US), the lesion is usually well defined and appears markedly hypoechoic or anechoic, occasionally mimicking a cyst [10, 29] (Fig. 1).
Although beyond the scope of the present article, but as a point of interest in the fascinating story of eye evolution, it turns out that invertebrate and vertebrate eyes are not as markedly split into two categories defined by having either ciliary or rhabdomeric photoreceptors or opsins as implied above.
Patients with defined NASH revealed markedly elevated hepatic chemerin expression compared to those with undefined or no NASH patients [ 41].
Of 410 markedly FOXP3-dependent transcripts, as defined by the expression microarray analysis, 90 (22%) were associated with at least one ChIP hit within the promoter coverage range of the tiling microarray.
Spleens were also discolored upon visual inspection and exhibited altered architecture upon histological analyses consisting of a markedly diminished red pulp and poorly defined lymphatic nodules (Fig. 3A-D).
However, applying the set of rules defined in phase I markedly improved the capacity of centers to detect the low to moderate T-cell responses.
However, one major concern about electrospun scaffolds for tissue repair and regeneration is that their small pores defined by densely compacted fibers markedly hinder cell infiltration and tissue ingrowth.
