Sentence examples for markedly decreased expression from inspiring English sources

Astrocytes expressing mhtt transform into reactive phenotype, which is characterized by markedly decreased expression of glutamate transporters (GLAST and GLT-1) and glutamate uptake.

The recellularized hearts also showed disarray of cardiomyocytes and markedly decreased expression of connexin43.

Ribozyme markedly decreased expression of TGF-β1 mRNA and protein in injured vessel.

Ribozyme markedly decreased expression of fibronectin, p27kip1, and CTGF mRNAs in injured vessel, whereas a mismatch ribozyme had no effect on these mRNAs.

In contrast, silencing SPHK1 by RNAi 2, which showed markedly decreased expression of SPHK1, dramatically enhanced UV- or adriamycin-induced cell death in glioma cells (Figures 2C).

Untreated SIV-infected, CD8+ cell-depleted animals demonstrated markedly decreased expression of SYN and MAP2 compared with uninfected controls, while MN-treated animals did not differ from uninfected controls.

Treatment with high dose (10 mg/kg) CsA markedly decreased expressions of Cytochrome C, AIF, and cleaved caspase-3, and inhibited apoptosis pathways.

CsA markedly decreased expressions of Nur77, p-Nur77, Bcl-2 and cyto C, and inhibited apoptosis.Improvement of neurological deficit, alleviation of brain edema and amelioration of EBI were obtained after prophylactic use of CsA.

injection of Aβ25 35 could markedly decrease expression of IDE and NEP, but CDS-treated reversed this phenomenon in a dose-dependent manner in mRNA level.

Immunohistochemical analysis of tumor sections showed that expression of UBXN2A markedly decrease expression of the cell proliferation marker Ki67.

Immunofluorescent staining showed that silencing profilin-1 gene expression markedly decreased the expression of profilin-1 (red fluorescence, Figure  5B) in the cytoplasm and improved F-actin redistribution (red fluorescence) in the presence of AGEs.