Sentence examples for markedly contributes from inspiring English sources

Amino acid P95 in p66 also markedly contributes to the dimerization binding energy.

The possible role of TRPA1 in migraine is supported by its co-expression in the same nociceptor subpopulation with CGRP, the neuropeptide that markedly contributes to migraine pain.

Periodontitis is a bacterially induced chronic inflammatory disease, and an imbalance of innate immune-defence system markedly contributes to the destruction of the periodontium [ 1].

DOI: http://dx.doi.org/10.7554/eLife.12002.002 De novo gene expression induced by noxious stimuli markedly contributes to the development of pain hypersensitivity (i.e., allodynia and hyperalgesia).

These data indicate that the absence of HSL alone markedly contributes to the reduction in neutral CE hydrolase activity, whereas ATGL together with HSL accounts for the main neutral TG hydrolase activities in macrophages.

Thus, they provide a long-lasting target to evaluate the effects of immunoneutralization. Accordingly, we recently reported that ProCT markedly contributes to mortality in experimental sepsis, and that immunoneutralization of this molecule diminishes mortality in our model of hamster sepsis [ 36].

This treatise and De motu cordis et aneurysmatibus (1728; "On the Motion of the Heart and on Aneurysms"), in which he discussed the various causes of heart enlargement and was the first to describe aneurysms of syphilitic origin, markedly contributed to knowledge of cardiac pathology.

The model compares very well with experimental results, confirming the formulated hypothesis that the internal layer damage does not markedly contribute to the quasi-isotropic laminate failure.

The further advancement of these prevascularization concepts and their adaptation to individual therapeutic interventions will markedly contribute to a broad implementation of tissue engineering applications into clinical practice.

The continuous development of these sophisticated approaches may markedly contribute to a broad implementation of spheroid-based tissue engineering in future regenerative medicine.

An officer of considerable ability, he won a noteworthy victory against a stronger French opponent, before embarking on a period of distinguished service off the Spanish and Portuguese coasts, working closely with the British generals fighting the Peninsular War, and markedly contributing to their success.