Sentence examples for markedly consistent with from inspiring English sources

High levels of eIF2 α-P were seen by western blotting of hippocampal protein samples from both ISRIB and vehicle-treated animals, but ISRIB treatment reduced levels of ATF4 markedly, consistent with its point of action downstream of eIF2 α-P, as previously described.

A higher dose of DMXAA does induce tumour regressions in TNFR1−/− mice (Table 2) and although time courses for 5HIAA production at higher doses have not been carried out, the dose response measured after 24 h increases markedly, consistent with the generation of a sustained 5HIAA response in TNFR1−/− mice at high dose.

Further analysis of ultrastable CpGs led us to identify a novel subset of CpG islands, 'ravines', which exhibit a markedly consistent pattern of low methylation with highly methylated flanking shores and shelves.

As a result, the expression of downstream substrates of β-catenin, including Axin-2, Cyclin D1 and c-Myc were markedly decreased consistent with the level of β-catenin (Fig. S4C).

The overall fold of Rv1155 strikingly resembles that of flavin mononucleotide-binding protein and pyridoxamine 5′-phosphate oxydase, but the architecture of the putative binding pocket is markedly different, consistent with the lack of color of Rv1155 and its inability to bind FMN.

Codons whose evolution is markedly more consistent with the alternate (compared with the null) hypothesis will exhibit large positive position-wise LRT statistics (hereafter LRT P ).

Gene expression associated with the complement pathway and oxidative metabolism is higher in uremia, while transcripts associated with the clathrin-coated vesicle endosomal pathway are markedly reduced consistent with a defect in phagocytosis.

Notably, the metformin-induced deceleration of the age increase in mortality rate was still present in aak-2 mutants, but initial mortality rates were markedly greater, consistent with increased sensitivity to metformin toxicity.

In contrast, markers of both the small and large subunit in the MRPS26 IP were markedly decreased, consistent with a substantial reduction in 28S assembly in the absence of ERAL1.

These results revealed that the duplicated chromosome 12 s in the UCSF-B7 and UCSF-B9 lines originated from different parents, and that the frequency and location of crossing-over events for the two parents was markedly different, consistent with a recent publication (Lee et al., 2011), and allowing us to infer that parent A was likely paternal and parent B was likely maternal.

There was hepatosplenomegaly and, of note, the pancreas was enlarged with markedly reduced attenuation consistent with being almost completely replaced by fat (See Figure  5).