Sentence examples for markedly changed in from inspiring English sources

The business of tending teeth has markedly changed in a generation or two, dentists say.

The landscape of clinical trial design has markedly changed in recent decades, with a clear emphasis on streamlining drug development towards specific patient populations and indications for investigational agents.

Moreover, alternative splicing of exons, including the model exon 3 of α-tropomyosin, was not markedly changed in mutant mice, suggesting that the role of raver1 for PTB-mediated exon repression is not absolutely required to generate splice variants during mouse development.

Comparative analysis of the respective spot patterns on 2-DE showed 146 spots that were markedly changed in TCC samples.

In conclusions, the microbial diversity and community structure markedly changed in different aged workshops which corresponded to the strong flavoring characteristics of Jinhua ham.

Alternations of levels of serum ALT and AST were markedly changed in a dose-dependent manner, but no significant differences were monitored in the levels of serum urea and creatinine.

However, we found that the levels of p53 and p21 did not markedly change in the presence of C75 or cerulenin in MEFs (Fig. 4A).

In contrast to vitamin C and the carotenoids, vitamin A and E showed no strong association with markers of adult or childhood socioeconomic position, and this did not markedly change in fully adjusted models.

Except for two patients, in which the IgG type anti-FN-Cit1035,1036 antibodies disappeared, the presence of these IgG antibodies did not markedly change in time.

In conclusion, modified ADAMTS1 expression resulted in markedly changed blood vessel morphology and altered TSP1 levels in the tumors.

Metformin markedly changed the folate composition in OP50, as detected by LC-MS/MS.