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We find that CAXIV and CAIX single ko EDL exhibit markedly but not maximally reduced lactate fluxes, whereas triple ko and double ko EDL show maximal or near-maximal inhibition of CA-dependent lactate flux.
Of interest, CIA was markedly but not completely suppressed in IL-17-deficient mice.
FOXP3 expression did not decrease, but E4BP4 increased markedly, but not significantly.
Moreover, CA074Me markedly, but not completely, reverted the pazopanib-induced autophagic cell death in BC cells.
For the pyrrolopyrimidines, the 4-chloro IVg confers markedly but not significantly higher activity than the 4-thio derivatives VIf.
Moreover, in patients with impaired ejection fraction (EF < 40%), sudden cardiac death was markedly but not significantly (P = 0.07) reduced by ∼45% in patients treated with ranolazine.
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I've eaten codfish Brás throughout New England, and the one served at Santos' is my favorite (some use rice instead of potatoes, and those versions are markedly inferior, but not one has as liberal a serving of well-flavored bacalao).
Using EMSA, a band shift for 13 bp polynucleotide was markedly observed, but not for 12 bp DNA.
These results show that the absence of Ncf1, and by extension the lack of functional NADPH oxidase, results in markedly reduced, but not completely absent, direct Treg suppression of Teffs.
KIF5B expression, as assessed by western blotting, was markedly reduced but not completely abolished (supplementary material Fig. S1B).
Metformin was reported to markedly suppress, but not completely abrogate, proliferation of breast cancer and cancer stem cells whilst being less toxic to normal stem cells [ 81].
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