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They observed that the signal generated by Integrin αV β3-targeted microbubble was markedly augmented at 4 days after ligation in FGF-2 treated group, coinciding with a greater angiogenic response.
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The kappa-selective agonists dynorphin A and dynorphin B, which exist in mossy fiber afferents to CA3 pyramidal neurons, also markedly augmented IM at low concentrations (20-100 nM).
Palmitate modestly increased cleaved caspase 3 at 3.3 mmol/l glucose; whereas, it markedly augmented caspase 3 activation at 22.2 mmol/l glucose (Figure 1B).
We found markedly augmented Stat6 binding to the gata3 S7 region in CD4+ T cells lacking Cbl-b at 30 min and 24 hr of stimulation with TCR/CD28 and IL-4, or increased binding of Stat6 to the Il9 promoter region in Cblb−/− CD4+ T cells at 30 min of stimulation with TCR/CD28, IL-4, and TGF-β.
Compared to sham controls, the level of inflammatory mediators in kidney parenchyma was markedly augmented in acute IR animals.
Results: During healing, the gene expression of several proinflammatory cytokines and Reg was markedly augmented.
This revealed that tamoxifen markedly augmented the specific phasic force of Mtm1−/y mice (+155%), reaching 61% of the force developed by WT mice.
ETT depletion markedly augmented sensitivity to pyrogallol-induced cell damage and death, reinforcing the physiologic antioxidant role of endogenous ET (Figure 5c and d).
The dissolution rate of tacrolimus was markedly augmented by the complexation with DM‐β‐CyD, reflecting its solubilizing activity.
As a result of the opposite effects of hemodilution on Pv aCO2 and Ca vO2, the ratio between both variables markedly augmented in the absence of anaerobic metabolism.
In addition, the effect of osmotic stretch on ERK activation was markedly augmented in cells expressing the AT1R-β-arrestin2 fusion compared with the wild type AT1R and completely blocked in cells expressing the AT1R-Gq fusion.
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