In contrast, shell lesions markedly attenuated the effect of d-amphetamine on increasing premature responses.
GGA markedly attenuated the morphine naloxone-induced withdrawal signs, including jumorphine naloxone-inducedawithdrawal
or polymyxin B (50 μM) treatment markedly attenuated the cardioprotective effect of angiotensin II preconditioning.
The presence of trastuzumab markedly attenuated the relative increase on p27 expression and the Bax:Bcl2 ratio induced by gefitinib.
In addition, the treatment with 25 mg/kg lacosamide markedly attenuated the activation of astrocytes and microglia in the ischemic CA1 region.
In addition, perfusion with IMD markedly attenuated the leakage of LDH, total protein and myoglobin from myocardia compared with I/R alone.
Repeated intrathecal injection with ATL markedly attenuated the CCI-induced thermal hyperalgesia and significantly inhibited NALP1 inflammasome activation, caspase-1 cleavage, and IL-1β maturation.
Preincubating EHTs with anti-miR-21-5p markedly attenuated the AE-induced contractile failure, cardiomyocyte hypertrophy and fibrotic response, recapitulating prior results in whole animals.
Both intravenous IgM and IgG preparations markedly attenuated the endotoxin-induced leukocyte adherence; however, only intravenous IgM was capable of further reducing venular leukocyte adherence, whereas IgG did not show protective effects compared with controls.
Rinsing the mouth with the antibacterial mouthwash prior to the nitrate load had no effect on nitrate accumulation in saliva or plasma but abolished its conversion to nitrite in saliva and markedly attenuated the rise in plasma nitrite.
Moreover, madecassoside markedly attenuated the content and deposition of β-amyloid peptide by inducing a decrease in the expression of amyloid protein precursor, β-site amyloid cleaving enzyme-1 and cathepsin B and an increase in the levels of neprilysin and insulin-degrading enzyme.
