Sentence examples for markedly ameliorate from inspiring English sources

This offers the possibility that immune treatment may markedly ameliorate the subsequent course, given the close association between endogenous insulin secretory capacity and glycemic control.

Moreover, CD4+ T cells, especially Th17 cells, seem to be more important than B cells, because administration of anti-CD4 mAb or anti-IL-17 mAb markedly ameliorate the progress of arthritis independent of anti-GPI antibodies titres [ 1, 2].

For example, in obese subjects the so-called 'inactive' GLP-1 metabolite (GLP-1 9-36 -NH2) has been reported to markedly ameliorate hepatic GLP-1 9-36 -NH2ion independent of its effects on islet cells, but concentrations of thasmetabeente wereportedeasured [ 32].

Histopathological examination of kidneys showed that CS-3150 mamelioratedliorated glomerulosclerosis, tubular injury and tubulointerstitial fibrosis.

Three-week pretreatment with rosuvastatin and/or ellagic acid markedly ameliorated HL- and isoproterenol-induced alterations in ECG, cardiac markers, oxidation markers, lipid profile and heart architecture.

In addition, C. molmol markedly ameliorated the antioxidant defenses and up-regulated Nrf2 and hemeoxygenase (HO -1 in tHO -1ver of DEN/PB-induced rathe

Researchers discovered that the neural toxicity from α-synuclein or htt-aggregates could be markedly ameliorated when TFEB is overexpressed or pharmacologically activated in PD or HD animal models, respectively (Decressac et al., 2013; Tsunemi et al., 2012).

The elevated rheumatoid factor (RF), prostaglandin E2 (PGE2), tumor necrosis factor-alpha (TNF-α), interleukin-17 (IL-17) and interleukin-1beta (IL-1β) levels and the lowered interleukin-4 (IL-4) level in arthritic rats were markedly ameliorated as a result of Ulva lactuca administration.

This demonstrates that the concomitant application of EcN during colitis induction with DSS markedly ameliorates the leakiness of the colonic epithelium.

The introduction of a neutralizing anti-PDGF antibody has shown that both mesangial proliferation and glomerulosclerosis can be markedly ameliorated in a rat glomerulonephritis model [14].

Transgenic expression of parkin markedly ameliorated all pink1 loss-of-function phenotypes, but not vice versa, suggesting that parkin functions downstream of pink1 [7], [8], [8].