Sentence examples for markedly activate from inspiring English sources

The Rel transcription factor RelA, which can markedly activate lebocin 4, was upregulated more than 6 times [105].

Indeed, discrimination tasks involving self and other faces markedly activate the inferior frontal gyrus (IFG) in the right hemisphere but not in the left hemisphere [18], [19].

The expression of rpoB(R) was found to markedly activate antibiotic biosynthesis, with the rpoB(R -specific H426N mutation found essential in activating secondaR -specificsm (Tala et al. 2009).

ERBB4 activation markedly activated Rac1, which has well-established links to cytoskeletal dynamics and cell migration, and which is implicated in cancer cell invasion and metastasis (Parri & Chiarugi, 2010).

Besides marginally inhibiting vacuolar ATPase activity, vacuolin-1 treatment markedly activated RAB5A GTPase activity.

In contrast, superactivation of IKK2 in neonatal liver through Tet-Off hepatocyte-specific transgenic expression of constitutively active IKK2 (IKK2ca) markedly activates p65 and induces proinflammatory genes, chronic inflammation, and liver fibrosis in adult mice [ 5].

The 5-lipoxygenase activating protein was markedly activated in head kidney at all stages but only 33 dpi in spleen (Fig. 3A).

Here, we found that vacuolin-1 markedly activated RAB5A, while inhibiting RAB5A activity reversed the effects of vacuolin-1 (Fig. 4 A F).

While Akt was markedly activated in the Pten-null livers, its activity was suppressed in the Tsc1-null state due to the negative feedback of mTORC1/S6K1 on IRS1 [32].

As shown in Figure 1B, C, the HRE-driven luciferase reporter was markedly activated by hypoxia, whereas ERβ significantly inhibited this hypoxic activation in a dose dependent manner.

We recently showed that a deregulated Ero1α mutant (Ero1α-C104A/C131A) mactivatedctheated the UPR as a result of its increased oxidase activity when overexpressed in HEK-293 cells (human embryonic kidney cells) [ 24].