Sentence examples for markedly abnormal from inspiring English sources

Markedly abnormal (grade 3 or grade 4) abnormalities were defined in accordance with the rheumatology common toxicity criteria, V.2.0.

Tumor microenvironment is markedly abnormal compared to that of nonmalignant tissues, and such abnormalities can enhance tumor metastasis and resistance to anticancer drugs.

Cases were classified by microbiological diagnosis, or in the absence of definitive microbiology as 1) normal CSF (neutrophils ≤ 1 × 10/L, lymphocytes ≤ 5 × 10/L, protein ≤ 0.5 g/dL, glucose ≥1.5 mmol/L), 2) minor abnormalities (neutrophils 2-5, lymphocytes 6-20, protein 0.51-1.0, glucose 1.0-1.49) or 3) markedly abnormal (neutrophils>5, lymphocytes>20, protein>1.0, glucose<1.0).

Ultrastructural analysis of the lesional dermis from bleomycin-injected wild-type mice revealed markedly abnormal arrangement of collagen fibrils, with normal large diameter collagen fibrils replaced by small collagen fibrils of 41.5 nm.

Despite the unremarkable formal RUQ ultrasound 42 h prior, POCUS at the time of her recurrent RUQ pain revealed a markedly abnormal gallbladder with wall thickening to 8 mm, narrowing of the gallbladder neck due to edema, a small non-obstructing gallstone, a normal common bile duct, subserosal edema, and pericholecystic fluid (Figure 3).

path·o·log·i·cal: being such to a degree that is extreme, excessive, or markedly abnormal.

b Post-contrast imaging of the same patient demonstrates areas of active contrast extravasation (arrows) within a markedly enlarged and abnormal appearing oesophagus.

In summary, the expression of RASSF1A was markedly reduced to an abnormal level or completely lost in primary GC compared with adjacent normal tissue, and was correlated to hypermethylation of the promoter of the RASSF1A gene.

When VBME and CCh were restudied for their influence on transit of charcoal meal in mice pretreated with the intraperitoneal injection of atropine, all the excitatory effects were markedly reduced and no abnormal behavior was observed in animals even afte four hours of injection.

In particular, RPL11 dysfunction results in abnormal erythrocyte development, markedly decreased progenitor cell proliferation, delayed erythroid differentiation, and markedly increased apoptosis [ 25].

Moreover, the incidence of abnormal spindles increased markedly at the 12 somite stage in the ewsr1 knockdown embryos compared to the bud stage, indicating the accumulation of mitotic defects during development.